New research model to aid search for degenerative disease cures

October 02, 2012

Efforts to treat disorders like Lou Gehrig’s disease, Paget’s disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.

The team, led by pediatrician Dr. Virginia Kimonis, has developed a genetically modified mouse that exhibits many of the clinical features of human diseases largely triggered by mutations in the valosin-containing protein.

The mouse model will let researchers study how these now-incurable, degenerative disorders progress in vivo and will provide a platform for translational studies that could lead to lifesaving treatments.

New research model to aid search for degenerative disease cures › 

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