melanoma

Melanoma Center

Melanoma, the most aggressive of all skin cancers, begins as a mole or other pigmented skin tissue. It accounts for less than 5 percent of U.S. skin cancer cases but the majority of all skin cancer deaths. If caught early, it is very treatable.

At the UC Irvine Health Melanoma Center, our nationally recognized physicians are leading experts in the treatment of melanoma and all types of skin cancers.

Our specialists are part of the Chao Family Comprehensive Cancer Center, which is Orange County's only National Cancer Institute-designated comprehensive cancer center and one of only 41 such facilities in the nation. They are at the forefront of research efforts to find new methods to treat and prevent melanoma.

To make an appointment, please call us at 714-456-8000 or fill out an appointment request form ›

At the UC Irvine Health Melanoma Center, our specialists use the latest technologies to diagnose skin disorders, including an advanced and painless imaging device called SIAscopy™.

The resulting high-resolution images are analyzed for indicators of various diseases — without the need for a biopsy. Leading-edge therapies include Mohs micrographic surgery, radiation therapy and chemotherapy.

We treat all cancers of the skin, including:
  • Melanoma
  • Basal cell carcinoma
  • Complex and advanced squamous cell carcinoma
  • Merkel cell carcinoma
  • Sarcoma of the skin
  • Spindle cell carcinoma
  • Cutaneous T-cell lymphoma
We offer the following treatments and services:
  • SIAscope mapping
  • Cryosurgery
  • Mohs microsurgery
  • Sentinel node biopsy
  • Lymphatic mapping
  • Systemic immune-based therapy
  • BRAF testing
  • Biochemotherapy
  • Interleukin-2 (immune tx)
  • Interferon (immune tx)

For skin cancers that have metastasized, we also offer cutaneous immune-based therapy.

Learn more about our treatments and services ›

At the UC Irvine Health Melanoma Center, our specialists take a multidisciplinary approach to treatment.

We work with each patient to develop a personalized treatment plan in a caring and healing environment. Our multidisciplinary team includes dermatologists, surgical oncologists, medical oncologists, radiation oncologists, plastic surgeons, nurses, case managers and other healthcare professionals.

Clinical trials

Our melanoma specialists participate in National Cancer Institute-sponsored clinical trials of the latest drugs and the most advanced methods for detecting and treating melanoma and other skin cancers.

This gives our patients have access to the best technologies and treatments, often long before they are available elsewhere.

Nationally recognized

Several of our Melanoma Center specialists have repeatedly been named among the Best Doctors in America®, representing the top five percent of their peers nationwide. The UC Irvine Health Chao Family Comprehensive Cancer Center has earned UC Irvine Medical Center recognition by U.S. News & World Report’s as one of the nation's best hospitals for cancer treatment.

The skin cancer specialists at the UC Irvine Health Melanoma Center take a cooperative approach to diagnosing and treating melanoma and other skin cancers.

Our multidisciplinary team, led by Dr. James G. Jakowatz, includes dermatologists, surgical oncologists, medical oncologists, radiation oncologists, plastic surgeons, nurses, case managers and other healthcare professionals. 

Highly trained and widely respected in their fields, our physicians offer patients the latest in diagnostic techniques and treatments. Many are also involved in leading-edge clinical trials.

Our melanoma specialists include:

Make an Appointment

714-456-8000