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Tests Offered

UC Irvine Health offers the latest in prevention and risk-associated testing. Our goal: to help you to live longer, stronger and healthier.

For Premier Health Exams, we offer a comprehensive package of laboratory tests for all patients. Depending on your risk-associated needs or desire to be even more thorough, we can also perform any of the advanced clinical, imaging and fitness tests described below under the supervision of your exam physician.

For Executive Physicals, tests are offered in a package tailored to ensure the long-term health and well-being of leadership team members. Each package is negotiated with your company, but included tests are often similar to the laboratory test package detailed below. Additional advanced tests may be provided as part of your company's plan or as recommended by your physician.

Here is a closer look at our comprehensive lab test package:

Laboratory markers for cardiac disease

  • Total cholesterol: The sum of all the cholesterol in your cholesterol carrying particles (HDL, LDL, etc.). Cholesterol can be deposited in arteries, causing plaques and creating risk for heart attack, stroke and more.
  • LDL cholesterol: The cholesterol inside of the “bad” cholesterol-carrying molecule.
  • HDL cholesterol: The cholesterol inside of the “good” cholesterol-carrying molecule
  • VLDL cholesterol: Another, less specific, type of “bad” cholesterol carrying molecule.
  • Triglycerides: Free floating fatty calories in the blood.
  • Non-HDL cholesterol: Total cholesterol minus the HDL cholesterol. A useful number to evaluate, but it’s not a direct measure of anything.
  • Apolipoprotein B: Attaches to the cholesterol carrying particles. It’s an indirect reflection of the LDL particle number and a great predictor of cardiovascular disease risk.
  • Lipoprotein (a): A genetic variant of LDL where a particle called apolipoprotein A gets attached. It’s a massive independent risk factor for cardiovascular disease, even for people who would otherwise have “normal” LDL cholesterol values.
  • LDL subclass: The average size of an LDL particle. This makes a difference in how likely it is to become embedded in an artery.
  • High sensitivity C-reactive protein: A marker of inflammation. It’s nonspecific, but inflammation generally points to an underlying problem, such as moderately advanced cardiovascular disease.

Laboratory markers for diabetes or diabetes risk

  • Hemoglobin A1c%: A value that allows us to reverse engineer a 90-day average blood sugar. We can see if you have normal sugars, are prediabetic or diabetic.
  • Glucose, blood serum: Usually acquired while fasting. It’s a “point in time” only, but elevated fasting blood sugars can be a simple way to identify diabetes risk and can support the hemoglobin A1c% findings.
  • Triglyceride-to -HDL ratio: Provides useful information for determining risk of metabolic syndrome and diabetes.
  • Insulin: A direct measure of the hormone level. Insulin is responsible for shuttling nutrients into cells. If the value is excessively high or low, it could suggest problems with insulin production or resistance and the existence of, or movement toward, diabetes.
  • HOMA-IR: A calculation that allows us to more accurately determine your insulin resistance. It incorporates the fasting blood sugar and insulin values.

Markers of thyroid function

  • Thyroid stimulating hormone (TSH): The brain makes this to tell the thyroid gland to produce new thyroid hormones. The value can help us look for high or low thyroid function.
  • Total T4: All of the T4 type of thyroid hormone. T4 is a more stable thyroid hormone variant, and is converted to T3 for many metabolic activities.
  • Free T4: Thyroid hormone can be bound to various carrier molecules. Bound thyroid hormone isn’t available for use. This looks a the amount of unbound T4 thyroid hormone.
  • Total T3: All of the T3 type of thyroid hormone. It’s the more powerful, active form.
  • Free T3: Thyroid hormone can be bound to various carrier molecules. Bound thyroid hormone isn’t available for use. This looks at the amount of unbound T3 thyroid hormone.
  • Reverse T3: T3 can have the iodine molecules on it in different positions. When in a certain configuration (the reverse T3 position), this molecule is metabolically inactive.

Markers of kidney function

  • Creatinine: A muscle breakdown product filtered by the kidneys. When your kidneys are working well, it does not “build up” in the blood.
  • Blood urea nitrogen: A metabolic breakdown product. BUN gets reabsorbed by the kidneys at a rate that’s dependent on effective blood flow. Slow blood flow and poor kidney function cause this value to rise.

Markers of liver function

  • Total protein: The sum of all of those proteins that are made in the liver. A healthy liver creates a predictable amount of proteins.
  • Albumin: A special type of protein made by the liver. It acts as a carrier molecule.
  • Aspartate aminotransferase (AST): A measure of liver injury.
  • Alanine aminotransferase (ALT): Another measure of liver injury.
  • Alkaline phosphatase: A nonspecific marker, but it can be elevated when there is liver injury due to blockages from masses and stones.
  • Total bilirubin: A blood breakdown product. It can be elevated for a number of reasons, one of which is liver dysfunction.

Sex hormone levels

  • Testosterone, total: Made in the testicles in men and ovaries in women. It’s primarily a male sex hormone, but it plays important roles in energy, metabolism and sexual health in both men and women.
  • Testosterone, free: Testosterone can be bound to various carrier molecules. This free fraction is the value of available testosterone.
  • Sex hormone binding globulin: The major blood protein molecules that testosterone and estrogen are bound by. High levels of this molecule can mean that even with normal total values, low available values can exist.
  • DHEA: The primary sex-steroid precursors in humans, made in the adrenals. Excess DHEA can cause a number of side effects, often more prominently in women than men. Too little can lead to low levels of sex hormones and their subsequent side effects.
  • DHEA-S: A metabolite of the primary sex-steroid precursor, and the form that most DHEA can be found in.
  • Estradiol: A type of estrogen, made in the ovaries in women. Its peripheral fat stores in both men and women.

Complete blood count (CBC)

  • White blood cells: Your infection-fighting army of cells.
  • Red blood cells: Carry hemoglobin, which transports oxygen.
  • Hemoglobin: Carries oxygen molecules.
  • Mean corpuscular volume (MCV): Average size of your red blood cells. This value can suggest a number of genetic or nutritional deficiencies.
  • Platelets: The liver tells the bone marrow to make platelets, which help a person stop bleeding. Low levels can lead to spontaneous bleeding or increased surgical or injury risk.
  • Additional CBC results: Differential analysis of the infection-fighting cells is also performed to look for specific abnormalities.

Electrolytes

Sodium, potassium, chloride, bicarbonate, magnesium and calcium are all measured and evaluated.

Vitamins

Vitamins D, B12 and folate are measured.

 

Here are optional tests you may choose to include as part of your exam:

  • Treadmill exercise stress test: An assessment of your exercise capacity. We push your body to its limits while being recorded on a continuous electrocardiogram heart monitor. Your fitness can actually help us predict your survival.
  • Carotid ultrasound IMT screening: A radiation-free imaging technology. We look directly into two major arteries of your body, the carotid arteries, to identify thickening and/or blockages. We then assess your risk of stroke and heart attack and act accordingly.
  • Functional movement screen: Seven fundamental movement patterns evaluated to identify imbalances, asymmetries and weaknesses. These can predispose you to developing an injury. As the only standardized musculoskeletal injury prevention screening tool available, this screening can help prevent you from becoming injured, as immobility breeds poor health.
  • Central blood pressure monitoring: A high-tech assessment of your arterial wall characteristics in the large, central arteries of your body. It’s completely noninvasive. This allows us to determine the age of your arteries relative to others and to trend how changes in your lifestyle alter your artery health.
  • Calculated markers of fitness and longevity: Includes two measurements. VO2 max (calculated) estimates how effectively your body can utilize oxygen in response to exercise demand. This can be compared to others in your age group. FIT score uses demographic and test-derived values to create a scientifically validated model that predicts your 10-year risk of death. This is important because it can be modified.
  • Vision assessment: Includes visual acuity, field of vision, color vision and ocular pressure (for glaucoma screening).
  • Hearing assessment: Identifies advanced hearing decline or asymmetrical hearing, which may be evidence of an underlying problem.
  • Strength and flexibility assessment: Measures push-ups, sit-ups, grip-strength and sit-and-reach. This is useful to assess your strength and flexibility and can be compared to others in your age group.
  • Pulmonary function test: Using a specialized spirometer, we determine your lung capacity and look for evidence of obstructive or restrictive changes in the lungs which can cause problems with breathing and, therefore, your lifestyle.
  • Body composition analysis: Our specialized equipment provides a variety of measurements including:

    • Your amount of body fat
    • How much of that body fat is of the dangerous “visceral” type around your organs
    • Your amount of muscle mass
    • Your level of hydration (by assessing total body water)

    Body composition is very important for your health. We give you all of the relevant details and track how to improve them over time as you execute your health-improvement action plan. 

Make an Appointment

714-427-5832