A Sequential 2-arm, Open-label Phase 1 Study to Evaluate the Effects of Encorafenib in Combination with Binimetinib on the Pharmacokinetics of Losartan, Midazolam, Caffeine, Omeprazole, and Dextromethorphan Administered in a Cocktail Approach and on the Pharmacokinetics of Rosuvastatin in Patients with BRAF V600-mutant Unresectable or Metastatic Melanoma or Other Advanced Solid Tumors

UCI-17-73
NCT99999999
Cancer - Colon, Cancer - Melanoma, skin, Cancer - Rectum
John P Fruehauf
Open
Treatment
LGX818, MEK162, Midazolam, Omeprazole, Prilosec
I
Adult
Local

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